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the intracellular monosaccharide modification central to O-GlcNAcylation signaling
used to build O-mannosyl glycopeptides relevant to α-dystroglycan biology
Fmoc-Ser(β-Glcα(1-4)Glc)-OH
/ Fmoc-Thr(GlcNAc(Ac)3-β-D)-OH / O-GlcNAc / Threonine
6-tetra-O-acetyl-β-D-galactopyranosyl)-L-tyrosine
GA631000: Fmoc-Thr(Man(Ac)4-α-D)-OH Pack Size:100 mg the intracellular monosaccharide modification centralC33H37NO14 671. 65 An Fmoc protected L threonine building block carrying an D mannose residue, designed for solid phase peptide synthesis (SPPS) of glycopeptides. The N Fmoc group is removed under standard base conditions (piperidine) during chain elongation, while the free carboxylic acid is available for coupling to the growing resin bound peptide. The sugar hydroxyl groups are protected as four acetate esters (Ac4), which keep the glycan inert
