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RPB1 CTD(Tn) glycopeptide
Core 1 Glycan (Serine)
For instance
C79H136N11NaO40S / 1935
The sulfo-NHS ester reacts with primary amines to form stable amide bonds
MV100040: Tris-GalNAc-β-Ala-PEG4-DBCO label-new RPB1 CTD(Tn) glycopeptideC94H149N13O35 2021. 25 A triantennary N acetylgalactosamine (Tri GalNAc) ligand presenting three GalNAc residues on a tris based branched scaffold, extended through a alanine linker and a discrete tetraethylene glycol (PEG4) spacer to a terminal dibenzocyclooctyne (DBCO) handle. The DBCO group reacts with azide functionalized partners via copper free strain promoted azide alkyne cycloaddition (SPAAC), forming stable 1,2,3 triazole linkages without a
