AG163050: β-D-GalNAc-Hexyl-NH-Cbz Pack Size:25 mg Galβ(1-3)GalNAc-α-1-O-Threonine (blocked amino acid)

Galβ(1-3)GalNAc-α-1-O-Threonine (blocked amino acid)

The sugar hydroxyl groups are protected as three acetate esters (Ac3)

66 / An Fmoc-protected L-threonine building block carrying an α-D-GalNAc residue

free acid) L-serine glycoamino acid carrying a Neu5Acα2-6GalNAcα disaccharide

O-glycosylation

AG163050: β-D-GalNAc-Hexyl-NH-Cbz Pack Size:25 mg Galβ(1-3)GalNAc-α-1-O-Threonine (blocked amino acid)C28H40N2O11 580. 6 A D N acetylgalactosamine (GalNAc) ligand equipped with an amine functionalized linker through a hexyl spacer. The primary amine can be covalently coupled with N hydroxysuccinimide (NHS) activated esters to form stable amide bonds, providing a straightforward route to conjugate the ligand onto NHS activated molecules and surfaces. The terminal amine is protected with a benzyloxycarbonyl (Cbz) group, which can be removed by