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Recent studies have also demonstrated that exendin-4 is mediated by Ca 2+ /calmodulin (CaM)-dependent protein kinase kinase/CAM-dependent protein kinase IV/prolactin regulatory element binding (CaMKK/CaMKIV/PREB) pathway increases liver ABCA1 expression and reduces cholesterol accumulation [71]

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The combination of these factors means tirzepatide users need to be more intentional about hydration than they were before starting treatment

Psychological support should continue alongside any pharmacological treatment, as medications alone do not address the underlying psychological, emotional, and behavioural factors that contribute to binge eating disorder

Burn body fat, reduce cravings and have more energy*