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Much of the safety data comes from animal studies, where researchers report on tolerance and effects in those models

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On Wegovy (semaglutide 2.4 mg, approved for chronic weight management): The FDA-approved prescribing information for Wegovy discloses that in the SELECT cardiovascular outcomes trial - a large study conducted in adults with established cardiovascular disease - hip and pelvis fractures were reported more often in female patients on Wegovy than in those on placebo: 1% (24/2,448) versus 0.2% (5/2,424)

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