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Gene expression analysis revealed no changes in HIF-1 mRNA, suggesting that GLP-1R signalling induces HIF-1 protein by a post-transcriptional mechanism (Fig
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We implemented the Bayesian Confidence Propagation Neural Network (BCPNN) for sensitivity analysis, with its specific computational formula detailed in Supplementary Table 1
Clinical trials have demonstrated that exendin-4-based therapies reduce HbA1c levels by approximately 9-16 mmol/mol (0.81.5%) when added to existing oral antidiabetic agents
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