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Neurologically, ALD/AMN can manifest with highly variable phenotypes, ranging from very aggressive and rapidly fatal inflammatory CNS demyelination in young boys to a more slowly progressive adult form either with cerebral white matter inflammatory lesions, or a more indolent progressive myelopathy and peripheral neuropathy (Moser, 1997)

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Recalculate syringe units for the new dose

According to UK guidance, treatment should be discontinued if at least 5% of initial body weight has not been lost after 12 weeks on the 3.0 mg daily dose