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Furthermore, constitutively activated nuclear factor erythroid 2-related factor 2 (NRF2) effectively suppressed lipid peroxidation, thereby preserving the effector functions of intratumoral CD8 + T cells and ultimately inhibiting tumor growth

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Then in 1953, Helmet Ferner at the University of Hamburg, established that two hormones were secreted by the A and B cells of the pancreatic islets