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Results vary based on dose, metabolism, and starting weight
Furthermore, because AST is a carotenoid with lipophilic properties, there is concern about its potential to accumulate in tissues with prolonged use
10.1161/CIRCULATIONAHA.117.028136 38
age 70%, with additional recommendations to aim for time below range of 12 weeks duration demonstrated reductions in HbA 1c from 9 to 5.1 mmol/mol (0.82% to 0.47%), with all approaches compared with a control diet
The key is to identify the subgroup that needs closer retinal follow-up
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