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10.4161/epi.4.6.9767 29
Cullen, J.J
Targeting EGFR-binding protein SLC7A11 enhancing antitumor immunity of T cells via inducing MHC-I antigen presentation in nasopharyngeal carcinoma
Due to intrinsic Cpf1 ribonuclease activity that facilitates crRNA processing and an array of donor DNA sequences for homology-directed repair of double-strand breaks generated by Cpf1, the multi-CRISPR/Cpf1 system is more efficient for multiplex deletion of up to four genes ( CRISPR-based genomic editing has been developed for multiplex gene editing in Bacillus (Lu et al., 2019)
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