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The specific approval depends on the type of HRT : local (vaginal) treatments are used primarily for GSM, while systemic forms (pills, patches, or gels) are prescribed for whole-body symptoms like hot flashes
For a 250 mcg dose: 0.25 mg 2.5 = 0.1 mL 100 = 10 units
In the formal human research record, three small Arizona Phase I-II studies (combined n=33 male research subjects) reported observations on skin darkening as a study endpoint [5] [6] [7]
Very common (more than 1 in 10): mild pain, redness, or swelling at injection site usually fades in a day
Duration of effect : Dementia develops over many years (often decades)
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