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Those with cardiovascular disease should also be under the close supervision of a professional, as the medication can influence cardiovascular health and blood sugar levels

Side effects tend to mirror those of GLP-1 agonists: Nausea Diarrhea Decreased appetite Possible gallbladder effects (as with all rapid weight loss) Minimal risk of hypoglycemia when used without insulin Importantly, GIP on its own does not cause hypoglycemia , making it a relatively safe therapeutic target

2019 Jan 10;14(1):e0210389

Therefore, oxidative change of this Met into methionine sulfoxide inactivates AAT as a serine protease inhibitor

There is not enough evidence to answer that