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A peer-reviewed overview in the International Journal of Molecular Sciences (Araj et al., Medical University of Warsaw, 2025) establishing Epithalon as a highly bioactive pineal tetrapeptide with documented mechanisms spanning telomere maintenance, epigenetic regulation, antioxidant defense, immune recalibration, and circadian rhythm restoration provides the scientific framework for all five mechanisms described in this section

1 2 Expert Review of Clinical Pharmacology

MalloyVLPerroneCEMattocksDALAblesGPCaliendoNSOrentreichDSet alMethionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice

This review highlights the unique potential of phytochemicals to advance the treatment of IC, offering opportunities to move beyond traditional therapies

March 9, 2023