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The backstory: Earlier last month, President Donald Trump announced a deal with Eli Lilly and Novo Nordisk to expand coverage and reduce prices for GLP-1 drugs
Clinical trials show that patients who escalate doses gradually experience fewer nausea episodes and better long-term adherence than those who jump to higher doses quickly
It is important to distinguish between dark urine caused by concentration (which appears deep yellow to amber and clears with increased fluid intake) and abnormal pigmentation suggesting pathology (such as tea-coloured urine indicating bilirubin, or red-brown urine suggesting blood or myoglobin)
Peroxisomes contribute to the acylcarnitine production when the carnitine shuttle is deficient
Weight may stabilize if nutrition and exercise are well managed
