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The enzymatic incretin degradation and immunological functions of DPP-IV are located at different sites within the enzyme ( Reference Yu, Yao and Chowdhury 44 ) which suggests that these functions may be independent of one another
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Swollen lymph nodes (lymphadenopathy) are not listed as a recognised adverse effect in the UK Summary of Product Characteristics or clinical trial data
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Moreover, in cardiomyocytes, SGLT2i inhibit late sodium current and calcium/calmodulin-dependent protein kinase II activity, promoting the contractionrelaxation cycle [114]
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