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They can reduce albuminuria (protein in the urine), which is a marker of kidney damage [8, 10]

Pharmacokinetic analysis Plasma concentration-time profiles were analysed in C57BL6J mice and Sprague Dawley rats by a non-compartmental method using sparse sampling in Pharsight Phoenix WinNonLin v.6.4 software, and the resulting terminal half-life ( T 1/2 ), maximum plasma concentration ( C max ), time for maximum plasma concentration ( T max ), and AUC from zero to last valid measurable concentration-time point (AUC 0-t ) were determined

interestingly two in silico screenings independently identified the COX-II inhibitor celecoxib as a potential anti-SARS-CoV-2 drug, and a very recent study still under peer review reports its beneficial effects plus famotidine in hospitalized patients (Tomera et al., 2020)

2024;bph.16363

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