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Following synthesis, purification is performed using high-performance liquid chromatography (HPLC) to achieve high purity

This review was not registered in any systematic review database

and by Health and Labour Sciences Research Grants from the Ministry of Health, Labour and Welfare of Japan (20042006 to H.S.) Ethics declarations Competing interests The authors declare no competing financial interests

Patients taking glucose-lowering medications should discuss allulose use with their GP or diabetes specialist before starting

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