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Below is a summary of available evidence for GLP-1 use in specific conditions, based on peer-reviewed literature as of 2024
The lack of upregulation of SLC22A5 at the gene level in CAR suggests that existing transporter capacities in bovine PBMC were adequate to handle the higher substrate flux from the extracellular to the intracellular space
Back Dupr, J (26 Sept 1964) 'An intestinal hormone affecting glucose disposal in man', The Lancet , 672-73
Angela Fitchs profile on the Obesity Medicine Association website
This led to the development of exenatide, a synthetic version of exendin-4, as the first GLP-1 agonist approved for treating type 2 diabetes in 2005
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