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In humans similar results were also obtained where the acute treatment of subjects with T2DM with dapagliflozin significantly improved systemic endothelial function and reduced both renal resistive index and aortic stiffness (56)

If the weekly maintenance dose of 1mg does not provide adequate control, the dose maybe increased up to 2.0 mg per week, based on the patients response and tolerance

Your provider will demonstrate proper subcutaneous injection technique, which involves injecting into the fatty tissue just beneath the skin in the abdomen, thigh, or upper arm

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The difference between a standard starting dose of 0.25 mg and the maximum maintenance dose of 2.4 mg is roughly a tenfold increase