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The article says these are peptides with high molecular weight and very high protein binding, properties that typically limit transfer into milk

In addition to advising patients to wait at least 30 min before taking other oral medications after oral semaglutide, increased clinical and laboratory monitoring should be considered when prescribing medications with a narrow therapeutic index or those that require clinical monitoring, such as levothyroxine [24, 75]

Monthly weight loss during this phase often ranges from two to four pounds, though individual rates vary based on starting weight, diet, and exercise habits

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