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GLP-1 receptor agonists (including medications like semaglutide, liraglutide, and tripeptide) mimic the action of this natural hormone

High-confidence substrates were identified by filtering for TMT-labeled neo-N termini significantly enriched in cells treated with active proteases compared to cells not treated with a protease or those treated with a catalytically inactive dead control

There are numerous other GLP-1 weight loss medications available, and many of them are frequently recommended for weight loss off-label

Systematic Review Registration: PROSPERO [CRD42024500551]

Most major telehealth platforms serve 40-50 states