Cynthia English, an OB/GYN in Fort Worth
Potential benefits: Initial trials of semaglutide showed that the drug not only could effectively control type 2 diabetes, but also led to an average weight loss of 8 to 10 pounds
4 Discussion This study demonstrates how C-terminal acylation of exendin-4 affects several GLP-1R pharmacological properties that are relevant to its therapeutic effect
Data on height, weight, body mass index (BMI), fasting glucose level, estimated glomerular filtration rate (eGFR), smoking status (never, ex-, and current smoker), and alcohol consumption (times per week) were extracted from the results of the national health screening examination conducted closest to the index date
Most are manageable, especially when treatment starts at a low dose and builds up gradually