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Accessed October 22, 2023
356 In DNA damageinduced conditions, frequent inactivation of the SLFN11 gene in tumor cells leads to the loss of its tRNAse activity, causing ribosome stalling and inhibition of protein translation
Seino Y, Yabe D, Sasaki T, Fukatsu A, Imazeki H, Ochiai H, et al
La dosis puede aumentarse gradualmente segn la tolerancia y respuesta clnica, hasta un mximo de 15 mg semanales para ambas indicaciones
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