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Several of these processes are controlled by DHHC-mediated S- palmitoylation of oncogenes or tumor suppressors, including growth factor receptors (e.g., EGFR), kinases (e.g., AKT), and transcription factors (e.g., -catenin)
30 for 5 fl
The theoretical concern about angiogenesis-driven tumor promotion persists despite absence of evidence specifically because the question has not been adequately studied in humans over meaningful timeframes