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Key limitations: Some compounds have direct human pharmacodynamic data
(7) hyperinsulinism as an energetic response to chronic cellular injury
J Biol Chem 293(8):28772887 Csibi A, Lee G, Yoon SO et al (2014) The mTORC1/S6K1 pathway regulates glutamine metabolism through the eIF4B-dependent control of c-Myc translation
While neither agent is specific for ferroptosis, these pre-clinical model studies suggest that a role for ferroptosis in the pathophysiology of IBD is worthy of greater consideration [37]
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