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These findings are consistent with studies in transgenic mouse models of tauopathies, where CR has been shown to alleviate tau pathology and improve cognitive function 67,68,69,70

SPR biosensing of human serum albumin binding affinity Interaction of peptidedrug conjugates with surface immobilized human serum albumin (HSA) (Sigma-Aldrich) was determined using surface plasmon resonance (SPR)

however, most studies have been of modest duration and conducted in diabetes populations rather than dedicated HF cohorts as continued pharmacovigilance and longer-term HF-specific safety data are needed

Because they are biologics and require strict temperature control, the risks of shipping them across borders are higher