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In the UK, adults with confirmed B12 deficiency and neurological symptoms typically receive hydroxocobalamin injections1 mg intramuscularly on alternate days until symptoms stabilise, followed by maintenance doses every two months
This can lead to a metallic taste due to irritation in the throat and mouth
In contrast, the passive diffusion process of B 12 absorption normally a very small portion of total absorption of the vitamin from food consumption may exceed the haptocorrin- and IF-mediated absorption when oral doses of B 12 are very large, with roughly 1% efficiency
Bacterial translocationImpact on the adipocyte compartment (in Eng)
Not recommended for use in individuals with asthma due to the possibility of increasing its symptoms
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