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Toxicity and adverse effects of Tamoxifen and other anti-estrogen drugs
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By age 40, the majority of people are making 30% less, and by 65, as much as 50% less and that is in healthy individuals
(They studied participants who did not have diabetes because the disease introduces more confounding variables.) The researchers suspected that people with the PAM variant would have lower levels of GLP-1 in their blood, perhaps because the unamidated form would be less stable
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