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7 Diagnosis A diagnosis of constipation is generally based on bowel habits, duration and severity of symptoms, and medical history

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This recycling process helps maintain redox homeostasis , the carefully controlled balance between oxidation and reduction reactions

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E -values, following VanderWeele and Dings approach, estimated the minimum strength of association needed by unmeasured confounders to fully explain observed associations, addressing potential biases from unmeasured confounding 53,54

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