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The critical role of this multi-faceted lactate shuttle is underscored by its validation across multiple tumor models (e.g., breast, prostate, osteosarcoma), where elevated MCT4 expression in CAFs is closely associated with enhanced tumor aggressiveness
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Diabetes (2016) 65(1):26975.10.2337/db15-0893 141 FischerELauterbachF
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The future of dual-agonist therapy Survodutide and tirzepatide represent two branches of the same evolutionary tree in metabolic medicine
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