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The hypothalamus, particularly the arcuate nucleus, contains GLP-1 receptors that modulate hunger and satiety signals

The pulsatile GH secretion induced by Tesamorelin remains physiological (preservation of endogenous pulses), distinguishing this approach from exogenous recombinant GH administration producing supra-physiological non-pulsatile levels

Series B (Methodological) 57 , 289300 (1995)

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