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Therefore, whilst palpitations can occur during Wegovy treatment, establishing causality requires careful clinical assessment and consideration of alternative explanations

Cost considerations also influence the switch

The Medicines and Healthcare products Regulatory Agency (MHRA) and the Summary of Product Characteristics (SmPC) for both medications do not list either treatment as a contraindication for the other

Glucagon receptor agonism triggers pro-emetic signaling in the area postrema of the brainstem and increases intestinal motility through direct smooth muscle stimulation (PMC12992036)

And as for those drugs, they really work, he says