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Autophagy-related proteins ATG4 and ATG7, important for autophagosome formation, are regulated by Trx (138,139)

Free Radic Biol Med 180(20):112 Murphy TH, Miyamoto M, Sastre A, Schnaar RL, Coyle JT (1989) Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

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2 In those with a genetic predisposition, psoriasis develops through a pathway of interactions following an environmental inflammatory trigger toward a keratinocyte, such as stress, trauma, or micro-organism action

Independent of other risk factors, a number of clinical studies have found that elevated levels of GGT increased the risk of metabolic syndrome [29, 30, 31]