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Data-sharing requests relating to data in this manuscript will be considered after the publication date and either (1) when this product and indication (or other new use) have been granted marketing authorization in both the US and Europe, or (2) when clinical development discontinues and the data will not be submitted to regulatory authorities

GLP-1 is one of the key hormonal components of the intestinal traffic control mechanism known as the ileal brake, which regulates the rate of nutrient transit and absorption

Retatrutide is a groundbreaking medication developed to support significant weight loss and improve metabolic health

The vanilloid receptor TRPV1 is tonically activated in vivo and involved in body temperature regulation

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