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Also, in DURATION-8, a significantly higher proportion of participants lost at least 5% of body weight when treated with the combination of exenatide QW and dapagliflozin as compared to either exenatide or dapagliflozin (30.7%, 14.1%, and 21.3%, respectively) 17

A recent analysis of FDA adverse event reporting system (FAERS) data from 2004 to 2020 revealed a notable association between GLP-1 RAs and malignant pancreatic neoplasms (proportional reporting ratio [PRR], 9.86) [52]

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However, according to the study from 2022 previously discussed, people experienced diarrhea for approximately 3 days after starting semaglutide treatment