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This is particularly important for patients suffering from severe spinal cord injuries, where conventional treatments often offer limited benefits

The identification of MSCs as multipotent stem cells was first accomplished by Friedenstein and colleagues in 1976, who isolated these cells from bone marrow [96]

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For musculoskeletal injury, including tendon tears, ligament sprains, and muscle strains, the preclinical evidence is most extensive and the extrapolated human dosing most confident

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