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The likelihood of renal failure is greatly increased by the presence of hypotension, decreased renal perfusion, dehydration, acidosis, or use of nephrotoxic drugs (22)

Time course of the melatonin-induced increase in glutathione peroxidase activity in chick tissues

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Additionally, the tissues (liver and pectoral muscle) were extracted and snap-frozen in liquid nitrogen before being transported to the laboratory and stored at 80 C until further analysis