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Ships within 48 hours Β· Estimated delivery Nov 1 - Nov 6
Suggested dosage: 2,500-5,000 IU daily as part of a multivitamin
Immunity 35 , 182193 (2011)
The result could position the drug as a treatment for MASH, which currently only has one FDA approved treatment in the market, Madrigals resmetirom (rezdiffra) , which achieves resolution of MASH and improves fibrosis, but does not have the added benefits of weight loss and glycemic control
Preclinical and clinical data suggest that FXR and PPAR dual modulators can improve insulin sensitivity, reduce hepatic steatosis, and attenuate fibrosis, which may complement the actions of GLP-1/GIP/GCG receptors agonists
Primary completion expected August 2030 (full study completion ~August 2032)
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