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We found between 43 and 2109 predicted neoepitopes with weak or strong HLA class I binding affinity in each patient (median 217) in early disease
This is why ED is often called the canary in the coal mine for cardiovascular disease
J Neurosci Res 89(4):481489 Abbas T, Faivre E, Hlscher C (2009) Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: Interaction between type 2 diabetes and Alzheimers disease
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