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In addition, the SUMMIT trial evaluates the effect of tirzepatide (the GLP-1/GIP dual receptor agonist) in people with obesity-related HFpEF (Clinicaltrials.gov ID NCT04847557)

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Amazing turn of events from Eli Lilly, and I believe highly relevant to our recent investigation which shows that GLP-1R and GIPR work primarily by engaging the AKAP SPHKAP, a prominent factor involved in bipolar disorder and schizophrenia: Fascinating

Transcriptional and epigenetic regulation of innate-like T lymphocyte development

Furthermore we suggest to update earlier studies by publishing follow-up data on neonatal outcome multiple years after maternal exposure