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The foundational obesity finding comes from Kraus and colleagues (Nature, 2014), who showed that knocking down NNMT protected mice against diet-induced obesity establishing NNMT as a metabolic target in the first place
Aleknaviciute G, et al
The science of metabolism has evolved, focusing on things like enzyme regulation and mitochondrial performance
Those with digestive challenges or dietary limitations may also see better results with this approach
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