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106 This derepresses Np63 expression, promoting lineage plasticity and the emergence of double-negative prostate cancer (DNPC) under androgen deprivation therapy

One central pathway is the PI3K/Akt cascade, which is a well-known regulator of cell metabolism, proliferation and survival (108), and can be directly stimulated by FSHR following direct interaction with 14-3-3 adaptor proteins (109)

Do not apply serum above 1% daily without cycling

Store at room temperature (15-30C) and protect from direct light

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