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Step 5: Provider-directed evaluation If constipation persists despite the steps above for more than 4 weeks, provider evaluation is appropriate
Ethics declarations Ethics approval and consent to participate All procedures described herein were approved by the Institutional Review Board for the Protection of Human Subjects of Baylor University (Protocol # 7920244) and Research Ethical Review Committee of Kyowa Hakko Kirin Co., Ltd
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Participants on the highest dose (120 mg twice daily) experienced an average HbA1c reduction of 1.16 percentage points and a weight loss of 4.17 kilograms
In addition, phentermine may cause headaches, dry mouth, nausea, vomiting, dizziness, diarrhea, and constipation, among other side effects
