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BPC-157 should be avoided in these populations

NICE technology appraisal TA875 (2023) recommends semaglutide 2.4 mg (Wegovy) as an adjunct to a reduced-calorie diet and increased physical activity for adults with a BMI of 35 kg/m or above (or 3034.9 kg/m in certain circumstances) alongside at least one weight-related comorbidity, when initiated within specialist weight management services

"While liraglutide isn't nearly as efficacious as semaglutide, the costs will likely come down as patents expire," says Whyte