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For instance, roGFP2-Orp1, the fusion of roGFP2 to the thiol peroxidase enzyme Orp1 is usually employed as a HO-sensitive probe and can be used to determine how chemicals induce or drugs decrease production of ROS in cells (AN252: Real-time monitoring of genetically encoded redox probes in mammalian cell monolayers)

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Smokers melanosis usually presents as diffuse but patchy and irregular pigmentation of the anterior facial maxillary and mandibular gingivae

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