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The AEs in REAC files are encoded by the preferred terms (PTs) in the Medical Dictionary for Regulatory Activities (MedDRA) terminology, which is comprised of 27 system organ classes (SOCs) ( Demographics (gender, age), reporting characteristics (reporting region, year, occupation of reporters), and indications of reports of GLP-1 RA-associated gastrointestinal toxicities were analyzed

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Can GLP-1 be used in type 1 diabetes

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In the widely cited STEP 1 trial published in the New England Journal of Medicine , participants receiving Wegovy lost an average of 14.9% of their body weight after 68 weeks, compared to 2.4% weight loss in the placebo group

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This pulsatile pattern exists for a biological reason

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Appetite and food noise usually return as the drug level declines, often within one to two months

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