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These disruptions in fuel homeostasis are not clearly related to their primary action of fluid management, raising concerns for patients with metabolic syndrome, in which high blood pressure coexists with obesity, insulin resistance, glucose intolerance and dyslipidemia

Sections were counterstained with haematoxylin (CS700, Dako-Agilent or RE7107-CE, Leica) and mounted with Mounting Medium, Toluene-Free (CS705, Dako-Agilent) using a Dako CoverStainer

Mitochondria-lysosome contact sites: emerging players in cellular homeostasis and disease