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This review synthesizes clinical and preclinical findings to elucidate the relationship between gut microbiota dysbiosis and aberrant inflammatory signaling in the periphery and central nervous system in schizophrenia
Looking to the future of what this means for GLP-1 deal making, the central message is that obesity is still very much a hot bed as there is need to invest in emerging modalities that can be combined/co-administered with GLP-1s and mitigate risks/target the residual unmet need associated with GLP-1s including the serious side effects such as nausea, vomiting, weight regain and excessive muscle loss
J., Lang, H
2FH and Supplementary Table S5)
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