Semaglutide, Retatrutide, and Tirzepatide belong to a class of drugs called Glucagon-like peptide-1 (GLP-1) receptor agonists
It is FDA-approved as Ozempic (2017), Wegovy (2021), and Rybelsus (2019, oral formulation), and serves as the reference compound for the broader class of long-acting GLP-1 receptor agonists
FDA Commissioner Marty Makary directly addressed social media influencers and telehealth companies in a JAMA article announcing the new ad policy changes, decrying the uptick in drug ads presented as entertainment. This represents a big change in how the FDA has viewed the regulation of drug compounders, which have typically been the purview of the states
Wine contains sulfites, which can contribute additional sulfur compounds to the digestive mix
While it is recommended to store compounded semaglutide in the refrigerator, recent studies indicate that it can be stable at room temperature for a limited time