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The primary objective was to demonstrate superiority of semaglutide 7.2 mg against placebo on weight loss
It is worth noting that the weight loss and metabolic improvements achieved with GLP-1 agonists may actually reduce overall thrombotic risk over time by addressing several modifiable risk factors
Further, many employers (as high as 59% of employers with at least 5,000 workers) that offered such coverage said that use of GLP-1 medications was higher than expected, and 66% of the largest employers said that covering such drugs for weight loss had a significant impact on their health plans prescription drug spending
Exenatide is based on exendin-4, a peptide found in Gila monster saliva, whilst semaglutide is a modified version of human GLP-1
By targeting the root causes of accelerated aging, GLP-1 therapy provides a multi-system approach to longevity
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